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KMID : 0361019960390040661
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Korean Journal of Otolaryngology - Head and Neck Surgery
1996 Volume.39 No. 4 p.661 ~ p.667
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Non-Hodgkin's Lymphoma of the Nasal Cavity, Paranasal Sinus and Nasopharynx
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김상연
이봉재/조용건/김재호/김상윤
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Abstract
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Non-Hodgkin's lymphoma of the nasal cavity and paranasal sinus is not common because these regions lack a typical lymphatic tissue, while Waldeyer's ring and cervical lymph nodes are the major site of head and neck lymphoma.
To understand the clinical and pathological characteristics of malignant lymphoma, the authors retrospectively reviewed the medical records, X-ray films, and pathological specimens of 13 cases of extranodal malignant lymphoma developed in the
nasal
cavity, paranasal sinus and nasopharynx.
The patients' age was evenly distributed in the range between 11 and 80 years.
Presenting symptoms were nasal obstruction in 7 cases(53%), rhinorrhea in 3 cases(23%), orbital swelling in 2 cases(16%), and earfullness in 1 case(8%) in the order of decreasing frequencry. According to the Working Formulation, the commonest
histopathologic type was diffuse large cell type in 9 cases969%), and the others were diffuse mixed small and large cell type(1 case, 8%), diffuse small cleaved cell(1 case, 85), and unconfirmed(2 cases, 15%). Combination of chemotherapy and
radiotherapy was given to 9 patients(69%), and only chemotherapy was given to 4 patients(31%).
Treatment outcomes of 8 cases, who were followed up for more than 12 months, revealed that 3 patients937%) with initial tumor of stageⅠand Ⅱ were alive alive with no evidence of disease, while 3 patients(37%) with stageⅢor IV died with
disease.
Our study suggests that early diagnosis using punch biopsy for the patients with suspicious symptoms and physical findings is mandatory to improve the prognosis of sino-nasal malignant lymphoma. (Korean J Otolaryngol 39 : 4, 1996)
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KEYWORD
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